- Tak-The main character and a shaman's apprentice. He uses his powers and Jujus to fix the problems that he causes. His personality and appearance has greatly changed since the games.
- Jeera-Tak's friend and the Cheif's daughter.
- Keeko-Tak's other friend who lives in a cave.
- Chief-The Chief of the Pupununu Village. He is a large man, with a big chin, and a very distinguished voice.
- Jibolba-The Shaman of the Village. He teaches Tak how to use magic, even though he does not always work out.
- Lok-The Resident Warrior of the Village. He is more of an anti-hero, many times causing problems to the village.
- Zaria-The Chief's other daughter. She is supposed to be the next chief of the village, although it is mentioned that she may not be.
- Slog-A beefy woman who has a crush on Lok.
- Traloc- A rival shaman of Jibolba's. He appears in one episode called "A Shaman's Shaman" where he tries to take over as Villiage Shaman and get rid of Jibolba, and take Tak under his wing. He proves to be a fraud when it's discovered he was using Ginto Powder to manipulate Tak's magic, which Jibolba had an allergy to. A cliffhanger was established at the end when he said he would be back, and he would be mad. He never showed up again. He's called Tlaloc in the original games.
- Tobar- A minor character from the games. He appears in the background of some episodes.
- Manny Rivera / El Tigre (from El Tigre: The Adventures of Manny Rivera)
- Frida Suárez (from El Tigre: The Adventures of Manny Rivera)
- Tyler Bowman (from Supernoobs)
- Jennifer Shope (from Supernoobs)
- Kevin Reynolds (from Supernoobs)
- Theodore "The Roach" Roachmont (from Supernoobs)
- Zenblock/Zen (from Supernoobs)
- Memnock/Mem (from Supernoobs)
- Belly Juju-A big purple Juju who talks with his belly. Same as game Juju.
- Bug Juju- A Juju that resembles a beetle.
- Bulldrafish Juju
- Caged Juju
- Dinky Juju
- Feet Juju
- Party Juju
- Psychic Juju
- Pugnacious Juju
- Really, Really Revolting Juju
- Spider Juju
- Vendor Juju
- Hal Sparks- Tak, Really, Really Revolting Juju
- Patrick Warburton- Lok
- Kari Whalgren- Jeera, Navis
- Rob Paulson- Party Juju
Differences From GamesEdit
There are many differences from the games. First, Tak, Lok, and Jibolba have personality and appearance changes. Dead Juju was re-named Party Juju and Mind-Reader Juju was re-named Psychic Juju. The Pupanunu Village became the Pupununu Village. Also, Tlaloc, the antagonist of the games, became Traloc.
- The only Jujus to not appear were Two-Headed Juju, Moon Juju, Flora, and Fauna
- The logo for the show just took the original game logo, and redid it to form a difference.
- Tak uses a whole new staff, amply named "The Power of Juju", instead of the Spirit Rattle from the first game, or the Staff of Dreams from the second.
- In the games, Lok tries to always be the big hero when he only does an average job, or he's just the comic relief. In the series, Lok just takes credit for all of Tak's heroics, making him more of a bragging jerk than a lovable oaf.
- It's argued that Jeera is the Expy (Similar) of Fauna, seeing as how she's a Tomboy like her.
- There has been talks about a television show for Tak since before the release of the first game. However, it was not announced until Tak: The Great Juju Challenge was being released.
- On September 21, 2016 Return of Tak and the Power of Juju en Teletoon renewed the series for a second season.